Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine ( The Intricate Gut Heart Connection; The Role of Gut Microbiota in the Pathogenesis of Cardiovascular Disease Frontiers Gut Metabolite Trimethylamine N Oxide in Atherosclerosis: From Mechanism to Therapy TMAO: The Gut Metabolite Linking Red Meat to Cardiovascular Disease
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