Signs You Might Be Low on Glutathione in Athletic Performance and How IV Therapy Could Make a Difference Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione Glutathione Understanding the Powerful Master Antioxidant Glutathione: What It Is, Why You Need It, How You Can Increase It The Amino Company