An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic This is a picosecond laser treatment of labial melanotic macules on the gingiva. Note the green flashes of the 532 nm laser as well as the immediate tissue whitening of the treated area. This Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Differential diagnosis of an oral mucosal pigmented lesion: a case of essential melanosis