Peptides are often well tolerated, but they can still cause temporary reactions while the body adapts. Some commonly reported effects include: BPC 157 headaches, nausea, increased appetite TB 500 Recognizing and Reducing Water Retention Water retention might sound like a minor inconvenience, but anyone who's experienced it knows it can feel like wearing a suit of armor made of water. It's Water Retention CJC 1295 + Ipamorelin Sculpt Your Body and Boost Energy