Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation GlyNAC looked like one of the most promising anti aging supplementsbut it probably isn't for most people. GlyNAC combines glycine and N acetylcysteine to provide two of the three building blocks needed to PDF) Glycine and Nacetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and GlyNAC Improves Physical Functioning and Cognition in Older Adults