What Caused These Multiple Hyperpigmented Macules of the Mouth? This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with Labial melanotic macule 3 sessions of Q switched Nd:YAG and the pigment has cleared beautifully. Precise targeting. Minimal downtime. Predictable results. #lippigmentation #lasertreatmentclinic