Glucose 6 phosphate Dehydrogenase (G6PD) Enzyme ROS Scavenger Biochemistry & Hematology Figure 1. G6pd Deficiency Does Not Affect the Cytosolic Glutathione or Thioredoxin Antioxidant Defense in Mouse Cochlea Journal of Neuroscience In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are G6PD deficiencydoes it alter the course of COVID 19 infections? Annals of Hematology Springer Nature Link