Glutathione S acetaminophen conjugate 64889 81 2 Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function, The conjugation of acetaminophen by glutathione and cytochrome P450. Download Scientific Diagram Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins &