l Carnitine Not Effective For Depression and Chronic Fatigue in MS and Neuromyelitis Optica How Acetyl L Carnitine Works HowStuffWorks A note about food and mood. I've spoken in YouTube videos before about the large effect my diet experiments have had my on mental function and wellbeing (depression, or its absence). Over Effectiveness of L carnitine Supplementation to Sertraline for Treatment of Major Depressive Disorder: A Double blind Randomized Placebo controlled Trial Global Journal of Medical Pharmaceutical and Biomedical Update