Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy Glucose 6 Phosphate Dehydrogenase Deficiency Does Glucose 6 Phosphate Dehydrogenase Deficiency Correlate with Increased Sensitivity to Cisplatin? A Case Report and a Narrative Literature Review Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst