IGF 1: Miracle Hormone or Health Hazard? Diet vs Disease Best time to take growth hormone? , Most athletes use it on an empty stomach, with the most common timing about an hour before bed., Consistency and timing make the difference., Watch the full HGH vs IGF 1 LR3: Scientific Comparison & Research Guide IGF 1 inhibits inflammation and accelerates angiogenesis via Ras PI3K IKK NF B signaling pathways to promote wound healing ScienceDirect