Gut Microbiome Derived Metabolite Trimethylamine N Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans Hypertension Simultaneous quantification of trimethylamine oxide and its precursors from gut microbial metabolic pathway The Role of Trimethylamine N Oxide as a Mediator of Cardiovascular Complications in Chronic Kidney Disease James Tomlins Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery Microbiome Springer Nature Link