Ipamorelin and CJC 1295 are almost always discussed together in research circles, and the reason comes down to receptor pharmacology. The two peptides work through entirely different but complementary mechanisms that produce a Ipamorelin 5 mg Peptide Gh Pathway & Endocrine Research PRG The most common GH releasing peptides: Ipamorelin A ghrelin receptor agonist that triggers short pulses of growth hormone release from the pituitary with minimal effects on cortisol, prolactin, or appetite. Tesamorelin CJC 1295 + Ipamorelin (no DAC)