Pentose Phosphate Pathway in Growth & Antioxidant Defense Creative Proteomics Molecular Vision: Engin, Mol Vis 2009; 15:855 860. Figure 2 Chronic Granulomatous Disease in Females: A Deficiency of Leukocyte Glutathione Peroxidase: New England Journal of Medicine: Vol 283, No 5 A clickable glutathione approach for identification of protein glutathionylation in response to glucose metabolism Molecular BioSystems (RSC Publishing)
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glutathione nadph G6PD Deficiency • Glucose-6-phosphate dehydrogenase deficiency • X-linked recessive disorder • Leads to low NADPH, impairing glutathione regeneration → RBCs are vulnerable to oxidative damage ⸻ Pathophysiology: In G6PD deficiency: • No