Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem Acetaminophen and hepatotoxicity. Acetaminophen (paracetamol) is Download Scientific Diagram View of Acetaminophen, the missing anion gap in the patient with metabolic acidosis The Southwest journal of medicine Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione depletion biomarkers ophthalmic acid and 5 oxoproline in humans and rats Integrative Biology (RSC
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paracetamol and glutathione depletion Illustration of the effects of acetaminophen on glutathione,