Glutamate: Synthesis, transport, and supplement interactions The glutathione cycle shapes synaptic glutamate activity PNAS Glutathione is such an important antioxidant in human physiology, meaning it acts to combat oxidative stress. Strategies for increasing glutathione include: Consume sulfur rich foods like cruciferous vegetables Ensure you get Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines ScienceDirect