Prolonged use of melatonin for the treatment of insomnia was associated with an increased risk for heart failure, hospitalization, and or all cause mortality, an observational study showed. Individuals with insomnia taking melatonin for Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease Journal of Neural Transmission Springer Nature Link Zetpil Calcium and Magnesium Suppository Zetpil A special update on the BIOCELL Special Issue, Melatonin and Mitochondria: Exploring New Frontiers, hosted by yours truly as managing guest editor, and the fabulous Dr. Russel J. Reiter as honorary guest