Effects of sex steroid hormones on lipid peroxidation and glutathione antioxidant system in rat skin Glutathione is often called the master antioxidant But it's actually regulated by melatonin (PMID: 20868358) Melatonin has been seen to have 10x the antioxidant capacity than glutathione Besides sleep, melatonin also regulates 16alpha Hydroxyestrone an overview ScienceDirect Topics Estrogen Carcinogenesis in Breast Cancer New England Journal of Medicine
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