Is it safe to give a lipotropic intramuscular injection and a vitamin B12 intramuscular injection at the same visit in a patient without allergies, severe hepatic disease, uncontrolled renal failure, pregnancy, nursing, Vitamin B 12 intramuscular injections are also used therapeutically to help restore energy and combat various symptoms related to such deficiencies. Vitamin B 12 is essential to the development of healthy blood cells, nerve B12 Shots at Home: How, Where & How Often to Inject Yourself AZ IV Medics Are B12 Shots Safe? ThinWorks