Exploring the Lean Phenotype of Glutathione Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles PLOS One 5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for Figure 1 from Lung glutathione and oxidative stress: implications in cigarette smoke induced airway disease. Semantic Scholar Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line Cell Death & Differentiation