Frontiers Treatments for Biomedical Abnormalities Associated with Autism Spectrum Disorder MTHFR Gene Polymorphisms: A Single Gene with Wide Ranging Clinical ImplicationsA Review You may have seen the acronym MTHFR, which stands for methylenetetrahydrofolate reductase. This is an enzyme that plays a role in processing the nutrient folic acid folate into a form the body can The MTHFR gene mutation is the world's biggest translation problem. If you're born with it, your body can't understand the language of standard vitamins. Even if you ingest them, they'll pass through,