5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. 5 1. Glutathione and Lipoic Acid D&PS NAC [N AcetylCysteine]** N AcetylCysteine [NAC] is not only a precursor for helping the body make more GLUTATHIONE [the body's most important antioxidant] but NAC is an anti inflammatory in its own right. When I Comprehensive metabolome analyses reveal N acetylcysteine responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin Metabolomics Springer Nature Link