How Many Vape Puffs Is One Cigarette? ARR Brand Nicotine formula used by e cigarette maker Juul is nearly identical to the flavor and addictive profile of Marlboro cigarettes : r science 1 electronic cigarette pod is roughly equal to 20 cigarettes' worth of nicotine, or 200 puffs. That's a lot! Make the choice not to let nicotine control your life. #EliminateTobacco and put Vaping vs smoking: nicotine equivalents explained