Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? Cigarettes Are In A Vape 5000 How Many Puffs Of An Electronic Vape Equal One Cigarette? Key Facts Explained Sanlei Vape Vape Equivalent To 200 Puffs Vaping is banned in our schools. Did you know: Most vapes contain high levels of nicotine (often without the person knowing). The nicotine in one e cigarette can equal to 50 cigarettes