How Many Vape Puffs Is One Cigarette? ARR Brand Public The amount of nicotine in an e cigarette can vary greatly. Youth may intake nicotine levels that are equivalent to multiple packs of cigarettes. To learn more about the highly addictive E Cigarettes Vaping with Juul & Other Electronic Cigarettes The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking